The Science of Medi-Weightloss®

The American Medical Association (2013) recognizes obesity as a disease that requires a range of medical interventions. Health problems, such as diabetes and cardiovascular disease, require the specialized, often individualized, care of a healthcare professional. This is why one- size-fits-all approaches to weight loss and weight maintenance often don’t result in long-term success. Research has shown that physician- supervised weight loss programs are an effective way to lose weight and maintain that weight loss over time (Jensen et al., 2013).

Developed and administered by healthcare experts, the physician-supervised Medi-Weightloss® Program is evidence-based to result in a successful lifestyle change. When administering the treatment, Medi-Weightloss® healthcare providers take each patient’s unique health profile into account, which is what makes us The One that Works!® In fact, our patients have lost nearly 3 million pounds nationwide since 2006.

Our Signature Supplements & Products are designed to enhance the weight loss treatment, assisting patients in reaching and maintaining their weight loss goals. Formulated to result in greater satiety, the low-calorie, high-protein products provide patients with quick, nutritious options that make weight loss simpler.The Medi-Weightloss® treatment guidelines are supported by industry sponsored research and are clinically demonstrated to be nutritious and beneficial for weight loss.

The Clinical Outcomes Overview is a collection of abstracts that include presented research of retrospective, controlled trials, and in-house scientific data on the efficacy of the program. We welcome your questions and feedback. For additional information, please email

American Medical Association (2013, June 18). AMA adopts new policies on second day of voting at annual meeting.
American Medical Association. Read the full article here.

Jensen, M.D., Ryan, D.H., Apovian, C.M., Loria, C.M., Ard, J.D., Millen, B.E., ... & Yanovski, S.Z. (2013).
2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity College of Cardiology , doi:10.1016/j.jacc.2013.11.004

The Scientific Advisory Board

In March 2012, Medi-Weightloss® held its inaugural meeting of the Scientific Advisory Board.

The board’s purpose is to critically review the effectiveness, safety, and added value of the Medi-Weightloss® treatment guidelines and products through outcomes research. This panel of physicians, scientists, and public health experts also assists in guiding the development of translational research studies that move scientific discoveries from university laboratories to the patient care setting.

The initiatives of this interdisciplinary team are shaped by the company’s dedication to quality assurance and the timely integration of clinical research findings into patient care. These efforts help assure that Medi-Weightloss® is and will always be The One that works!® – for patients, for physicians, and for investors.

Board Members

  • Edward A. Zbella, MD, CPI, FACOG, FACS, Chief Medical Officer, Medi-Weightloss® Corporate Headquarters, Tampa, FL, US
  • Macklin E. Guzman, DHSc, MPH, Vice President of Research and Development/Chief Compliance Officer, Medi-Weightloss® Corporate Headquarters, Tampa, FL, US
  • Jennifer L. Nguyen, PhD, MPH, CPH, Postdoctoral Associate, The Minority Cancer Research and Training (MiCaRT) Center, University of Florida, Orlando, FL, US
  • Eva Imperial, MD, Family Physician (specializing in women’s health), Vista Women’s Healthcare, Columbia, SC, US
  • Frank J. Troncale, MD, FACG, Medical Director & Physician, Medi-Weightloss®, Orange, CT, US; Affiliations include: Yale- New Haven Hospital/Saint Raphael Campus, Milford Hospital and Yale-New Haven Hospital.
  • Suzi Hancock, RNC-OB, WHNP-BC, Nurse Practitioner/Office Manager, Medi-Weightloss®, Waco, TX, US
  • Jamie King, APN, Nurse Practitioner, Medi-Weightloss®, Peoria, IL, US
  • Christina Holub, PhD, MPH, Research Associate, Institute of Behavioral and Community Health, San Diego State University, San Diego, CA, US
  • Elise Schram, MPH, CHES, Program Assistant for Special Projects, Illinois Public Health Institute, Chicago, IL, US

Do you suffer from MetS?

This study assesses the impact of a physican-supervised nonsurgical medical weight management program on the prevalence of MetS and it's key indicators. Download the article.



Appetite Suppressant Medication vs. Herbal Supplement

Patients who are prescribed phentermine have been found to lose weight at a greater rate than patients who are prescribed phendimetrazine or an herbal appetite suppressant. Download the phentermine research.

Signature Shakes & Bars

Patients who purchase Signature Shakes & Bars have been found to lose more weight than patients that do not. Download Signature Shakes & Bars research.

Body Composition

Patients have been found to lose more body fat, as a percentage of lost weight, during the 4th through 12th weeks of the Medi-Weightloss® Program. Click here to download the research.

Changes in Type 2 Diabetes Risk

Many patients who are retested after having lost 25 - 35 lbs have been found to have lowered their risk of type 2 diabetes. Download diabetes research.


Many patients who attend the Medi-Weightloss® Program have been found to improve their blood pressure levels. Download blood pressure research.

Indirect Calorimetry

Patients who receive a BMR test with an indirect calorimeter at their Initial Consultation have been found to reduce their fat mass. Download BMR research.

Appetite Suppressant Medication

Patients who are prescribed appetite suppressants have been found to lose 45% more weight than patients who qualify for but decide not to take the medication. Click here to download the research.

Weekly Injections

Patients who frequently receive a midweek injection have been found to lose more weight than patients who do not. Click here to download the research.

Program Adherence

Patients who visit their Medi-Weightloss® location approximately once per week have been found to lose a greater median percentage of their starting body weight than patients to don’t visit as often. Click here to download the research.

Social Support

Patients who enroll with a partner have been found to lose more weight. Click here to download the research.

Clinical Outcomes


Clinical Outcomes Brochure

is available for download.


Signature Patient Website

Explore the various weight loss exercises available at our Signature Patient Website.